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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmedpharm</journal-id><journal-title-group><journal-title xml:lang="ru">Фармация и фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pharmacy &amp; Pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2307-9266</issn><issn pub-type="epub">2413-2241</issn><publisher><publisher-name>Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical Univer</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.19163/2307-9266-2018-6-5-462-474</article-id><article-id custom-type="elpub" pub-id-type="custom">pmedpharm-326</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАРМАКОГНОЗИЯ, БОТАНИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHARMACOGNOSY, BOTANY</subject></subj-group></article-categories><title-group><article-title>МИКРОМОРФОЛОГИЧЕСКИЙ АНАЛИЗ НАДЗЕМНЫХ ОРГАНОВ  MARRUBIUM ALYSSON L. ФЛОРЫ ТУНИСА</article-title><trans-title-group xml:lang="en"><trans-title>MICROMORPHOLOGICAL ANALYSIS OF THE AERIAN ORGANES OF MARRUBIUM ALYSSON L. FROM FLORA OF TUNISIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9409-9344</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Серебряная</surname><given-names>Ф. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Serebryanaya</surname><given-names>F. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Серебряная Фатима Казбековна – кандидат фармацевтических наук, доцент кафедры фармакогнозии и ботаники; научный сотрудник Эколого-ботанической станции БИН РАН.</p><p>357532, г. Пятигорск, пр. Калинина, 11;</p><p>197376, г. Санкт-Петербург, ул. Профессора Попова, д. 2.</p></bio><bio xml:lang="en"><p>Serebryanaya Fatima Kazbekovna – Candidate of sciences (Pharmacy), associate professor of the Chair of pharmacognosy and botany; researcher of the ecological and botanical station of Botanical institute of Russian Academy of Sciences.</p><p>11, Kalinin ave., Pyatigorsk, Russia, 357532; </p><p>2, Professor Popov St., St. Petersburg, Russia, 197376.</p></bio><email xlink:type="simple">f.k.serebryanaya@pmedpharm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайер</surname><given-names>Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zayer</surname><given-names>G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайер Гази – студент 3 курса.</p><p>357532, г. Пятигорск, пр. Калинина, 11.</p><p> </p></bio><bio xml:lang="en"><p>Zayer Ghazi – 3rd -year student (Pharmacy).</p></bio><email xlink:type="simple">ghazizayer@outlook.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пятигорский медико-фармацевтический институт – филиал ФГБОУ ВО «Волгоградский государственный медицинский университет» Минздрава России; Эколого-ботаническая станция Федерального государственного бюджетного учреждения науки Ботанический институт им. В.Л. Комарова Российской академии наук (БИН РАН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pyatigorsk medical and Pharmaceutical Institute – branch of Volgograd State Medical University; Ecological and botanical station of Botanical institute of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Пятигорский медико-фармацевтический институт – филиал ФГБОУ ВО «Волгоградский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pyatigorsk medical and Pharmaceutical Institute – branch of Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>10</day><month>11</month><year>2018</year></pub-date><volume>6</volume><issue>5</issue><fpage>462</fpage><lpage>474</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Серебряная Ф.К., Зайер Г., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Серебряная Ф.К., Зайер Г.</copyright-holder><copyright-holder xml:lang="en">Serebryanaya F.K., Zayer G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmpharm.ru/jour/article/view/326">https://www.pharmpharm.ru/jour/article/view/326</self-uri><abstract><p>Проведены морфолого-анатомические исследования шандры Алиссон (Marrubium alysson L.), произрастающей в естественных условиях на территории Республики Тунис. Цель исследования – провести сравнительные эколого-морфологические исследования надземных органов Marrubium alysson, изучить анатомическое строение элементов каулифолиарной системы, в том числе листовой пластинки, черешков, элементов побега, анатомическое строение эпидермы листовой пластинки. Материалы и методы. В качестве объекта исследования использовали высушенную траву и гербарные образцы шандры Алиссон (Marrubium alysson L.), произрастающей в естественных условиях на территории Республики Тунис. Исследование проводилось морфолого-анатомическими и гистохимическими методами. Результаты и обсуждение. Проведены сравнительные эколого-морфологические исследования. Изучено анатомическое строение элементов каулифолиарной системы, в том числе листовой пластинки, черешков, элементов побега. Изучено анатомическое строение эпидермы листовой пластинки. Обнаружен диацитный тип устьичного аппарата, многочисленные ветвистые трихомы, с многоклеточным основанием, расположенные как на верхней, так и на нижней стороне листа. Проведенные исследования являются фрагментом комплексных исследований перспективных сырьевых растений флоры Туниса. Заключение. Проведены сравнительные эколого-морфологические исследования, морфолого-анатомические исследования, изучено анатомическое строение стебля, черешка листа и листовой пластинки, а также строение верхней и нижней эпидермы листа. Обнаружен диацитный тип устьичного аппарата, многочисленные ветвистые трихомы, расположенные как на верхней, так и на нижней стороне листа. Колленхима расположена субэпидермально в зоне стебля, черешка листа и в зоне центральной жилки листовой пластинки. Выявленные признаки могут быть включены в проекты нормативной документации на растительное сырье.</p></abstract><trans-abstract xml:lang="en"><p>The micromorphological investigations of Marrubium alysson L. growing on the territory of the Tunisian Republic have been conducted. The aim of the study was to conduct comparative ecological and morphological researches of Marrubium alysson aerian parts, to study an anatomical structure of caulifoliary system elements including stems, petioles, leaf margins a structure of the epidermis. Materials and methods. As an object of the research, dried-up herb and herbarium specimens of Marrubium alysson L., growing on the territory of the Tunisian Republic, were used. The micromorphological investigations were conducted by morphological and histochemical methods. Results and discussion. Comparative ecological and morphological researches have been conducted. The anatomic structure of the elements of the caulifoliary system including stems, petioles, leaf margins has been studied. The anatomic structure of the epidermis has been studied, too. The diacytic type of the stomatal apparatus, numerous branched trichomes with multicellular basis, located both on top and lower leaf parts have been found out. The conducted researches are a fragment of complex researches of perspective raw plants of Tunisian flora. Conclusion. Comparative eсological and micromorphological researches have been conducted, the anatomic structure of the stems, petioles, leaf margins, and also the epidermis structure of top and lower leaf parts has been also carried out. The diacytic type of the stomatal apparatus, trichomes with multicellular basis located both on top and lower leaf parts have been found out. The collenchyme is located in the subepidermal zone of a stem, petioles and in the zone of the central vein of a limb. The revealed signs can be included into product specification files on herbal raw materials</p></trans-abstract><kwd-group xml:lang="ru"><kwd>шандра Алиссон</kwd><kwd>Marrubium alysson L.</kwd><kwd>флора Туниса</kwd><kwd>эколого-морфологические исследования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Marrubium alysson L.</kwd><kwd>Tunisian flora</kwd><kwd>ecological and morphological investigations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ОФС.1.5.3.0003.15 Техника микроскопического и микрохимического исследования лекарственного растительного сырья и лекарственных растительных препаратов. Государственная фармакопея Российской Федерации ХIII изд. 2015. [Электронный ресурс]. 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