<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pmedpharm</journal-id><journal-title-group><journal-title xml:lang="ru">Фармация и фармакология</journal-title><trans-title-group xml:lang="en"><trans-title>Pharmacy &amp; Pharmacology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2307-9266</issn><issn pub-type="epub">2413-2241</issn><publisher><publisher-name>Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical Univer</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.19163/2307-9266-2019-7-5-244-259</article-id><article-id custom-type="elpub" pub-id-type="custom">pmedpharm-510</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. ОБЗОРЫ, ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES. REVIEWS, LECTURES</subject></subj-group></article-categories><title-group><article-title>Фенольные соединения лавра благородного (обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Phenolic compounds of laurus nobilis (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0960-6127</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коновалов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Konovalov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коновалов Дмитрий Алексеевич – доктор фармацевтических наук, профессор, заведующий кафедрой фармакогнозии, ботаники и технологии фитопрепаратов.</p><p>357532, Ставропольский край, Пятигорск, пр. Калинина, 11.</p><p>Researcher ID: B-7017-2017</p><p>Scopus Author ID: 56436041900</p></bio><bio xml:lang="en"><p>Dmitry A. Konovalov - Doctor of Science (Phamacy), Professor, Head of Department of Pharmacognosy, Botany and Technology of Phytopreparation.</p><p>11, Kalinin ave., Pyatigorsk, Stavropol region, 357532.</p><p>Researcher ID: B-7017-2017</p><p>Scopus Author ID: 56436041900</p></bio><email xlink:type="simple">d.a.konovalov@pmedpharm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиева</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alieva</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алиева Наида Махмудовна – старший преподаватель кафедры нормальной физиологии.</p><p>367000, Республика Дагестан, Махачкала, пл. Ленина, 1.</p></bio><bio xml:lang="en"><p>Naida M. Alieva - Senior Lecturer, Department of Normal Physiology.</p><p>1, Lenin sq., Makhachkala, Dagestan republic, 367000.</p></bio><email xlink:type="simple">nasuhov.5@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Волгоградский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pyatigorsk Medical and Pharmaceutical Institute – branch of Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Дагестанский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dagestan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>04</day><month>12</month><year>2019</year></pub-date><volume>7</volume><issue>5</issue><fpage>244</fpage><lpage>259</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коновалов Д.А., Алиева Н.М., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Коновалов Д.А., Алиева Н.М.</copyright-holder><copyright-holder xml:lang="en">Konovalov D.A., Alieva N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmpharm.ru/jour/article/view/510">https://www.pharmpharm.ru/jour/article/view/510</self-uri><abstract><p>Одним из самых известных растений семейства лавровые (Lauraceae) является лавр благородный (Laurus nobilis L.). Целью исследования являлся обзор научной информации по изучению фенольных соединений дикорастущего и культивируемого лавра благородного.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Исследование проводилось с использованием информационно-поисковых (PubMed, ScholarGoogle) и библиотечных баз данных (eLibrary, Cyberleninca), а также приложения ResearchGate для семантического поиска. Методы исследования – анализ и обобщение научной литературы за период с 2000 года по настоящее время.</p></sec><sec><title>Результаты</title><p>Результаты. Представленные в обзоре данные показывают, что листья, плоды и побеги лавра благородного являются ценными источниками фенольных соединений, таких как фенольные кислоты, флавоноиды, проантоцианидины. Количественное содержание этих групп веществ варьирует в зависимости от места сбора, источника сырья (культивируемые или дикорастущие растения), времени (фазы) его заготовки, способа сушки, извлечения из сырья и т.д. Фенольные соединения проявляют выраженную антиоксидантную и антирадикальную активность, оказывают ингибирующее влияние на продукцию оксида азота, натрий-калиевую аденозинтрифосфатазу, на линии опухолевых клеток (HeLa, MCF7, NCI-H460 и HCT15), характеризуются антибактериальным действием в отношении грамположительных и грамотрицательных бактерий.</p></sec><sec><title>Заключение</title><p>Заключение. Анализ доступной научной информации показал, что фенольные соединения лавра благородного являются одной из основных групп действующих соединений этого растения. Использование этих данных важно для разработки новых эффективных лекарственных средств на основе сырья лавра благородного.</p></sec></abstract><trans-abstract xml:lang="en"><p>One of the most famous plants of the laurel family (Lauraceae) is Laurus nobilis L.</p><p>The aim of the study was to review scientific information on the study of phenolic compounds of wild-growing and cultivated Laurus nobilis L.</p><sec><title>Materials and methods</title><p>Materials and methods. The study was performed using information retrieval (PubMed, ScholarGoogle) and library databases (eLibrary, Cyberleninca), as well as ResearchGate application for semantic search. The research methods are analysis and synthesis of the scientific literature data for the period from 2000 up to the present.</p></sec><sec><title>Results</title><p>Results. The data presented in the review show that leaves, fruits, and shoots of Laurus nobilis L. are valuable sources of phenolic compounds, such as phenolic acids, flavonoids, and proanthocyanidins. The quantitative content of these groups of substances varies depending on the collecting ground, the source of raw materials (cultivated or wild plants), the time (phase) of their harvesting, the method of drying, extraction from raw materials, etc. Phenolic compounds exhibit a pronounced antioxidant and antiradical activity, have an inhibitory effect on NO production, sodium-potassium adenosine triphosphatase, on tumour cell lines (HeLa, MCF7, NCI-H460 and HCT15), and are characterised by an antibacterial action against gram-positive and gram-negative bacteria.</p></sec><sec><title>Conclusion</title><p>Conclusion. The analysis of the available scientific information showed that the phenolic compounds of Laurus nobilis L. are one of the main groups of the active compounds of this plant. The use of this information is essential for the development of new effective medicines based on the raw materials of Laurus nobilis L..</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>лавр благородный</kwd><kwd>Laurus nobilis</kwd><kwd>фенольные соединения</kwd><kwd>количественное определение</kwd><kwd>антиоксидантная</kwd><kwd>противораковая активность</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Marzouki, H., Piras, A., Salah, K. B. H., Medini, H., Pivetta, T., Bouzid, S., Falconieri, D. Essential oil composition and variability of Laurus nobilis L. growing in Tunisia, comparison and chemometric investigation of different plant organs // Natural product research. 2009. Vol. 23. Is. 4. P. 343-354.</mixed-citation><mixed-citation xml:lang="en">Marzouki H, Piras A, Salah KBH, Medini H, Pivetta T, Bouzid S, Falconieri D. Essential oil composition and variability of Laurus nobilis L. growing in Tunisia, comparison and chemometric investigation of different plant organs. Natural product research. 2009;23(4):343-54.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Barla, A., Topcu, G., Oksuz, S., Tumen, G., Kingston, D.G.I. Identification of cytotoxic sesquiterpenes from Laurus nobilis L.// Food Chemistry. 2007. Vol. 104, Is. 4. P. 1478-1484.</mixed-citation><mixed-citation xml:lang="en">Barla A, Topcu G, Oksuz S, Tumen G, Kingston DGI. Identi-fication of cytotoxic sesquiterpenes from Laurus nobilis L. Food Chemistry. 2007;104(4):1478-84.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Fang, F., Sang, S., Chen, K.Y., Gosslau, A., Ho, C.-T., Rosen, R.T. Isolation and identification of cytotoxic compounds from Bay leaf (Laurus nobilis) // Food Chemistry. 2005. Vol. 93, Is. 3. P. 497-501.</mixed-citation><mixed-citation xml:lang="en">Fang F, Sang S, Chen KY, Gosslau A, Ho CT, Rosen RT. Iso¬lation and identification of cytotoxic compounds from Bay leaf (Laurus nobilis). Food Chemistry. 2005;93(3):497-501.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ivanoic, J., Misin, D., Ristic, M., Pesic, O., Zizovic, I. Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.) - chemical composition and antibacterial activity // Journal of the Serbian Chemical Society. 2010. Vol. 75. P. 395-404.</mixed-citation><mixed-citation xml:lang="en">Ivanoic J, Misin D, Ristic M, Pesic O, Zizovic I. Supercritical CO2 extract and essential oil of bay (Laurus nobilis L.) - chemical composition and antibacterial activity. Journal of the Serbian Chemical Society. 2010; 75:395-404.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ouchikh, O., Chahed, T., Ksouri, R., Taarit, M.B., Faleh, H., Abdelly, C., Kchouk, M.E., Marzouk, B. The effects of extraction method on the measured tocopherol level and antioxidant activity of L. nobilis vegetative organs // Journal of Food Composition and Analysis. 2011. Vol. 24. P 103-110.</mixed-citation><mixed-citation xml:lang="en">Ouchikh O, Chahed T, Ksouri R, Taarit MB, Faleh H, Abdelly C, Kchouk ME, Marzouk B. The effects of extraction method on the measured tocopherol level and antioxidant activity of L. nobilis vegetative organs. Journal of Food Composition and Analysis. 2011;24:103-10.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Conforti, F., Statti, G., Uzunov, D., Menichinia, F. Comparative chemical composition and antioxidant activities of wild and cultivated Laurus nobilis L. Leaves and Foeniculum vulgare subsp. piperitum (Ucria) Coutinho Seeds // Biological &amp; Pharmaceutical Bulletin. 2006. Vol. 29. P. 2056-2064.</mixed-citation><mixed-citation xml:lang="en">Conforti F, Statti G, Uzunov D, Menichinia F. Comparative chemical composition and antioxidant activities of wild and cultivated Laurus nobilis L. Leaves and Foeniculum vulgare subsp. piperitum (Ucria) Coutinho Seeds. Biological &amp; Pharmaceutical Bulletin. 2006;29:2056-64.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ozcan, B., Esen, M., Sangun, M.K., Coleri, A., Caliskan, M. Effective antibacterial and antioxidant properties of methanolic extract of Laurus nobilis seed oil // Journal of Environmental Biology. 2010. Vol. 31. P. 637-641.</mixed-citation><mixed-citation xml:lang="en">Ozcan B, Esen M, Sangun MK, Coleri A, Caliskan M. Effective antibacterial and antioxidant properties of methanolic extract of Laurus nobilis seed oil. Journal of Environmental Biology. 2010;31:637-41.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Polovka, M., Suhaj, M. Detection of caraway and bay leaves irradiation based on their extracts antioxidant properties evaluation // Food Chemistry. 2010. Vol.119. P. 391-401.</mixed-citation><mixed-citation xml:lang="en">Polovka M, Suhaj M. Detection of caraway and bay leaves irradiation based on their extracts antioxidant properties evaluation. Food Chemistry. 2010;119:391-401.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Speroni, E., Cervellati, R., Dall'Acqua, S., Guerra, M.C., Greco, E., Govoni, P., Innocenti, G. Gastroprotective effect and antioxidant properties of different Laurus nobilis L. leaf extracts // Journal of Medicinal Food. 2011. Vol. 14. P. 499-504.</mixed-citation><mixed-citation xml:lang="en">Speroni E, Cervellati R, Dall'Acqua S, Guerra MC, Greco E, Govoni P, Innocenti G. Gastroprotective effect and antioxidant properties of different Laurus nobilis L. leaf extracts. Journal of Medicinal Food. 2011;14:499-504.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ramos, C., Teixeira, B., Batista, I., Matos, O., Serrano, C., Neng, N.R., Nogueira, J.M.F., Nunes, M.L., Marques, M. Antioxidant and antibacterial activity of essential oil and extracts of bay leave Laurus nobilis Linnaeus (Lauraceae) from Portugal. Natural Product Research. 2012. Vol. 6. P. 518-529.</mixed-citation><mixed-citation xml:lang="en">Ramos C, Teixeira B, Batista I, Matos O, Serrano C, Neng NR, Nogueira, JMF, Nunes ML, Marques M. Antioxidant and antibacterial activity of essential oil and extracts of bay leave Laurus nobilis Linnaeus (Lauraceae) from Portugal. Natural Product Research. 2012;6:518-529.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Dall'Acqua, S., Cervellati, R., Speroni, E., Costa, S., Guerra, M.C., Stella, L., Greco, E., Innocenti, G. Phytochemical composition and antioxidant activity of Laurus nobilis L. leaf infusion // Journal of Medicinal Food. 2009. Vol. 12. P. 869-876.</mixed-citation><mixed-citation xml:lang="en">Dall'Acqua S, Cervellati R, Speroni E, Costa S, Guerra MC, Stella L, Greco E, Innocenti G. Phytochemical composition and antioxidant activity of Laurus nobilis L. leaf infusion. Journal of Medicinal Food. 2009;12:869-76.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ghannadi A. Lauri Folium. In: "Iranian Herbal Pharmacopoeia". Tehran: Publications of Iranian Ministry of Health (2002).</mixed-citation><mixed-citation xml:lang="en">Ghannadi A. Lauri Folium. In: "Iranian Herbal Pharmacopoeia". Tehran: Publications of Iranian Ministry of Health. 2002.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ramling P., Meera M., Priyanka P. Phytochemical and Pharmacological Review on Laurus Nobilis // Int. J. of Pharm. and Chem. Sci. 2012. Vol. 1, Is. 2. P. 595-602.</mixed-citation><mixed-citation xml:lang="en">Ramling P, Meera M, Priyanka P. Phytochemical and Phar-macological Review on Laurus Nobilis. Int J of Pharm and Chem Sci. 2012;1(2):595-602.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Esra K., Ilkay O., Erdem Y. Evaluation of Some Plants Used in Turkish Folk Medicine for Their Anti-inflammatory and Antinociceptive Activities // Pharmac. Biol. 2007. Vol. 45, Is. 7. P. 547-555.</mixed-citation><mixed-citation xml:lang="en">Esra K, Ilkay O, Erdem Y. Evaluation of Some Plants Used in Turkish Folk Medicine for Their Anti-inflammatory and An-tinociceptive Activities. Pharmac Biol. 2007;45(7):547-55.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Bilen S., Bulut M. Effect of Laurel (Laurus nobilis) on the non-Specific immune responses of rainbow trout (Oncorhynchus mykiss, Walbaum) // J. of Animal and Veterinary Advances. 2010. Vol. 9, Is. 8. P. 1275-1277.</mixed-citation><mixed-citation xml:lang="en">Bilen S, Bulut M. Effect of Laurel (Laurus nobilis) on the non-Specific immune responses of rainbow trout (Oncorhynchus mykiss, Walbaum). J of Animal and Veterinary Advances. 2010;9(8):1275-7.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Shin J., Oh K., Lee S., Nam K., Koo U., Kim K.H., Mar W. Neuroprotective Effect of the n-Hexane Extracts of Laurus nobilis L. in Models of Parkinson's Disease // Biomol. Ther. 2011. Vol. 19, Is. 1. P. 118-125.</mixed-citation><mixed-citation xml:lang="en">Shin J, Oh K, Lee S, Nam K, Koo U, Kim KH, Mar W. Neuroprotective Effect of the n-Hexane Extracts of Laurus nobilis L. in Models of Parkinson's Disease. Biomol Ther. 30. 2011;19(1):118-25.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Rizi M.V. Chemical Composition and Larvicidal Activity of the Essential Oil of Laurus nobilis L. from Iran. Iranian Journal of Pharmaceutical Sciences // Iranian J. of Pharmac. Sci. 2009. Vol. 5, Is. 1. P. 47-50.</mixed-citation><mixed-citation xml:lang="en">Essential Oil of Laurus nobilis L. from Iran. Iranian Journal of Pharmaceutical Sciences. Iranian J of Pharmac Sci. 2009;5(1):47-50.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Saab A.M., Tundis R., Loizzo M.R., Lampronti I., Borgatti M., Gambari R., Menichini F., Esseily F., Menichini F. Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells // Natural Product Research. 2012. Vol. 26. P. 1741-1745.</mixed-citation><mixed-citation xml:lang="en">Saab AM, Tundis R, Loizzo MR, Lampronti I, Borgatti M, Gambari R, Menichini F, Esseily F, Menichini F. Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells. Natural Product Research. 2012;26:1741-5.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Kaileh, M., W. V. Berghe, E. Boone, T. Essawi, G. Haegeman. Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity // Journal of Ethnopharmacology. 2007. Vol. 113, Is. 3. P. 510-516.</mixed-citation><mixed-citation xml:lang="en">Kaileh M, Berghe WV, Boone E, Essawi T, Haegeman G. Screening of indigenous Palestinian medicinal plants for potential anti-inflammatory and cytotoxic activity. Journal of Ethnopharmacology. 2007;113(3):510-6.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Kalaldeh, J.Z., Abu-Dahab, R. Afifi F.U. Volatile oil composition and antiproliferative activity of Laurus nobilis,Origanum syriacum, Origanum vulgare, and Salvia triloba against human breast adenocarcinoma cells // Nutrition Research. 2010. Vol. 30, Is. 4. P. 271-278.</mixed-citation><mixed-citation xml:lang="en">Al-Kalaldeh JZ, Abu-Dahab R. Afifi FU. Volatile oil com¬position and antiproliferative activity of Laurus nobilis, - Origanum syriacum, Origanum vulgare, and Salvia triloba against human breast adenocarcinoma cells. Nutrition Research. 2010;30(4):271-8.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">de Corato, U., O. Maccioni, M. Trupo, G. Di Sanzo. Use of essential oil of Laurus nobilis obtained by means of a supercritical carbon dioxide technique against post harvest spoilage fungi // Crop Protection. 2010. Vol. 29, Is. 2. P. 142-147.</mixed-citation><mixed-citation xml:lang="en">de Corato U, Maccioni O, Trupo M, Di Sanzo G. Use of essential oil of Laurus nobilis obtained by means of a supercritical carbon dioxide technique against post harvest spoilage fungi. Crop Protection. 2010;29(2):142-7.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Millezi, A. F., D. S. Caixeta, D. F. Rossoni, M. G. Cardoso, and R. G. Piccoli. In vitro antimicrobial properties of plant essential oils Thymus vulgaris, Cymbopogon citratus and Laurus nobilis against five important foodborne pathogens // Ciencia e Tecnologia de Alimentos. 2012. Vol. 32. P. 167-172.</mixed-citation><mixed-citation xml:lang="en">Millezi AF, Caixeta DS, Rossoni DF, Cardoso MG, Piccoli RG. In vitro antimicrobial properties of plant essential oils Thymus vulgaris, Cymbopogon citratus and Laurus nobilis against five important foodborne pathogens. Ciencia e Tecnologia de Alimentos. 2012;32:167-72.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Adwan, G., Mhanna M. Synergistic effects of plant extracts and antibiotics on Staphylococcus aureus strains isolated from clinical specimens // Middle-East Journal of Scientific Research. 2008. Vol. 3. P. 134-139.</mixed-citation><mixed-citation xml:lang="en">Adwan G, Mhanna M. Synergistic effects of plant extracts and antibiotics on Staphylococcus aureus strains isolated from clinical specimens. Middle-East Journal of Scientific Research. 2008;3:134-9.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Hussaini, R., Mahasneh A.M. Microbial growth and quorum sensing antagonist activities of herbal plants extracts // Molecules. 2009. Vol. 14, Is. 9. P. 3425-3435.</mixed-citation><mixed-citation xml:lang="en">Al-Hussaini R, Mahasneh AM. Microbial growth and quorum sensing antagonist activities of herbal plants extracts. Molecules. 2009;14(9):3425-35.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Fukuyama N., Ino C., Suzuki Y., Kobayashi N., Hamamoto H., Sekimizu K., Orihara Y. Antimicrobial sesquiterpenoids from Laurus nobilis L. // Natural Product Research. 2011. Vol.25, Is. 14. P. 1295-1303.</mixed-citation><mixed-citation xml:lang="en">Fukuyama N, Ino C, Suzuki Y, Kobayashi N, Hamamoto H, Sekimizu K, Orihara Y. Antimicrobial sesquiterpenoids from Laurus nobilis L. Natural Product Research. 2011;25(14):1295-303.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Otsuka, N., M.-H. Liu, S. Shiota et al. Anti-methicillin resistant Staphylococcus aureus (MRSA) compounds isolated from Laurus nobilis // Biological and Pharmaceutical Bulletin. 2008. Vol. 31, Is. 9. P. 1794-1797.</mixed-citation><mixed-citation xml:lang="en">Otsuka N, Liu MH, Shiota S, et al. Anti-methicillin resistant Staphylococcus aureus (MRSA) compounds isolated from Laurus nobilis. Biological and Pharmaceutical Bulletin. 2008;31(9):1794-7.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Liu, M.-H., N. Otsuka, K. Noyori et al. Synergistic effect of kaempferol glycosides purified from Laurus nobilis and fluoroquinolones on methicillin-resistant Staphylococcus aureus // Biological and Pharmaceutical Bulletin. 2009. Vol. 32, Is. 3. P. 489-492.</mixed-citation><mixed-citation xml:lang="en">Liu MH, Otsuka N, Noyori K, et al. Synergistic effect of kaempferol glycosides purified from Laurus nobilis and fluoroquinolones on methicillin-resistant Staphylococcus aureus. Biological and Pharmaceutical Bulletin. 2009;32, (3):489-92.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Огай М.А., Степанова Э.Ф. Разработка и исследование гипогликемического фитосбора // Вестник Воронежского государственного университета. Серия: Химия. Биология. Фармация. 2006. №. 2. С. 332-333.</mixed-citation><mixed-citation xml:lang="en">Ogay MA, Stepanova EF. Razrabotka i issledovaniye gipoglikemicheskogo fitosbora [Development and research of a hypoglycemic phytosborne]. Bulletin of the Voronezh State University. Series: Chemistry. Biology. Pharmacy. 2006;2:332-3.Russian.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Огай М.А., Степанова Э.Ф., Ларионов Л.П., Петров А.Ю. Фармакологические исследования и технология фитогелей для коррекции последствий сахарного диабета // Вестник Воронежского государственного университета. Серия: Химия. Биология. Фармация. 2009. № 2. С. 171-173.</mixed-citation><mixed-citation xml:lang="en">Ogay MA, Stepanova EF, Larionov LP, Petrov AYu. Farmakologicheskiye issledovaniya i tekhnologiya fitogeley dlya korrektsii posledstviy sakharnogo diabeta [Pharmacological research and phytogel technology for the correction of diabetes mellitus]. Bulletin of Voronezh State University. Series: Chemistry. Biology. Pharmacy. 2009;2:171-3. Russian.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Пат. 2071783 Россия, МКИ 6 А 61 К 35/78. Способ получения средства для лечения сахарного диабета / Бабякин А.Ф., Найданова Л.Ф., Мазуров В.И., Руженков Д.В., Кириченко Н.Н. № 93044820/14; Заявл. 07.09.93; Опубл. 20.01.97, Бюл. № 2.</mixed-citation><mixed-citation xml:lang="en">Pat. 2071783 Russia, MKI 6 A 61 K 35/78. Sposob polucheniya sredstva dlya lecheniya sakharnogo diabeta [A method of obtaining funds for the treatment of diabetes]. Babyakin F, Naydanova LF, Mazurov VI, Ruzhenkov DV, Kirichenko NN. No. 93044820/14; Claim 09/07/93; Publ. 01/20/97, Bull. Number 2. Russian.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Патент на изобретение. Смирнов В.М. Биологически активная пищевая добавка и способ повышения умственной и физической работоспособности человека // Номер патента: 2176895. Страна: Россия. Год: 2001. Дата регистрации: 22.11.1999. Номер заявки: 99124708/13. МПК: 7A 23L 1/30 A, 7A 61K 35/78 B.</mixed-citation><mixed-citation xml:lang="en">Pat. 2176895 Russia, IPC: 7A 23L 1/30 A, 7A 61K 35/78 B.32. Biologicheski aktivnaya pishchevaya dobavka i sposob povysheniya umstvennoy i fizicheskoy rabotosposobnosti cheloveka [Dietary supplement and method of increasing mental and physical health of a person]. Smirnov VM. Date of registration: 11.22.1999. Application Number: 99124708/13.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Diaaz-Maroto, M.; Rez-Coello, M.; Cabezudo, M. Effect of drying method on the volatiles in bay leaf (Laurus nobilis L.) // J. Agric. Food Chem. 2002. Vol. 50. P. 4520-4524.</mixed-citation><mixed-citation xml:lang="en">Diaaz-Maroto M; Rez-Coello M; Cabezudo M. Effect of drying method on the volatiles in bay leaf (Laurus nobilis L.). J Agric Food Chem. 2002;50:4520-4.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Насухова, Н.М., Коновалов Д.А. Динамика накопления эфирного масла в листьях лавра благородного // Вестник Волгоградского государственного медицинского университета. 2014. № S. С. 94-95.</mixed-citation><mixed-citation xml:lang="en">Nasukhova NM, Konovalov DA. Dinamika nakopleniya efirnogo masla v list'yakh lavra blagorodnogo [The dynamics of the accumulation of essential oil in the leaves of laurel noble]. Bulletin of the Volgograd State Medical University. 2014;S:94-5.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Насухова, Н.М., Коновалов Д.А. Сесквитерпеновые лактоны листьев и плодов Laurus nobilis L. (лавра благородного) // Фармация и фармакология. 2014. № 2 (3). С. 23-33.</mixed-citation><mixed-citation xml:lang="en">Konovalov DA, Nasuhova NM. Sesquiterpene lactones of leaves and fruits of Laurus nobilis L. Pharmacy &amp; Pharmacology. 2014;2(2(3)):23-33. Russian. https://doi.org/10.19163/2307-9266-2014-2-2(3)-23-33</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">El-Feraly, S.; Benigni, D. Sesquiterpene lactones of Laurus nobilis leaves // J. Nat. Prod. 1980. Vol. 43. P. 527-531.</mixed-citation><mixed-citation xml:lang="en">El-Feraly S; Benigni D. Sesquiterpene lactones of Laurus nobilis leaves. J Nat Prod. 1980;43:527-31.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Matsuda, H.; Kagerura, T.; Toguchida, I.; Ueda, H.; Morikawa, T.; Yoshikawa, M. Inhibitory Effects of sesquiterpene from Bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction // Life Sci. 2000. Vol. 66. P. 2151-2157.</mixed-citation><mixed-citation xml:lang="en">Matsuda H; Kagerura T; Toguchida I; Ueda H; Morikawa T; Yoshikawa M. Inhibitory Effects of sesquiterpene from Bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction. Life Sci. 2000;66:2151-7.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Сенченко С.П., Насухова Н.М., Агова Л.А., Коновалов Д.А. Использование ВЭЖХ и капиллярного электрофореза для количественного определения костунолида и дегидрокостуслактона в листьях лавра благородного // Вестник Волгоградского государственного медицин¬ского университета. 2014. № 4 (52). С. 18-20.</mixed-citation><mixed-citation xml:lang="en">Senchenko SP, Nasuhova NM, Agova LA, Konovalov DA. Using HPLC and capillary electrophoresis for quantifying costunolide and dehydrocostuslatone in Laurel leaves. Bulletin of the Volgograd State Medical University. 2014;4(52):18-20. Russian.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Yoshikawa, M.; Shimoda, H.; Uemura, T.; Morikawa, T.; Kawahara, Y.; Matsuda, H. Alcohol absorption inhibitors from Bay leaf (Laurus nobilis): Structure-requirements of sesquiterpenes for the activity // Bioorg. Med. Chem. 2000. Vol. 8. P. 2071-2077.</mixed-citation><mixed-citation xml:lang="en">Yoshikawa M,Shimoda H, Uemura T, Morikawa T, Kawahara Y, Matsuda H. Alcohol absorption inhibitors from Bay leaf (Laurus nobilis): Structure-requirements of sesquiterpenes for the activity. Bioorg. Med. Chem. 2000;8:2071-7.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Rasul, A., Parveen, S., &amp; Ma, T. (2012). Costunolide: A novel anti-cancer sesquiterpene lactone // Bangladesh Journal of Pharmacology, 7(1), 6-13.</mixed-citation><mixed-citation xml:lang="en">Rasul A, Parveen S, Ma T. Costunolide: A novel anti-cancer sesquiterpene lactone. Bangladesh Journal of Pharmacology.2012;7(1):6-13.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Lin, X., Peng, Z., &amp; Su, C. (2015). Potential anti-cancer activities and mechanisms of costunolide and dehydroco stuslactone. International journal of molecular sciences, 16(5), 10888-10906.</mixed-citation><mixed-citation xml:lang="en">Lin X, Peng Z, Su C. Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone. International journal of molecular sciences. 2015;16(5):10888-906.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Emam, A.M., Mohamed, M.A., Diab, Y.M., Megally, N.Y. Isolation and structure elucidation of antioxidant compounds from leaves of Laurus nobilis and Emex spinosus // Drug Discoveries &amp; Therapeutics, 2010. Vol. 4. P. 202-207.</mixed-citation><mixed-citation xml:lang="en">Emam AM, Mohamed MA, Diab YM, Megally NY. Isolation and structure elucidation of antioxidant compounds from leaves of Laurus nobilis and Emex spinosus. Drug Discoveries &amp; Therapeutics. 2010;4:202-207.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Kaurinovic, B., Popovic, M., Vlaisavljevic, S. In vitro and in vivo effects of Laurus nobilis L. leaf extracts // Molecules. 2010. Vol. 15. P. 3378-3390.</mixed-citation><mixed-citation xml:lang="en">Kaurinovic B, Popovic M, Vlaisavljevic S. In vitro and in vivo effects of Laurus nobilis L. leaf extracts. Molecules. 2010;15:3378-90.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Нестерова, О. В., Доброхотов, Д. А., &amp; Дидманидзе, И. О. (2015). Анализ фитохимических свойств и некоторых показателей качества листьев лавра благород¬ного // Вопросы обеспечения качества лекарственных средств, (1), 23-30.</mixed-citation><mixed-citation xml:lang="en">Nesterova OV, Dobrokhotov DA, Didmanidze IO. Analysis of phytochemical features and some of the quality index¬es of Laurus nobilis leaves. Questions of quality of medicines. 2015;1(6):23-30. Russian.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Kang, Yu K.W., Jun W.J., Chang I.S., Han S.B., Kim H.Y., Cho H.Y. Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis // Biol. Pharm. Bull. 2002. Vol. 25, Is.1. P. 102-108.</mixed-citation><mixed-citation xml:lang="en">Kang Yu KW, Jun WJ, Chang IS, Han SB, Kim HY, Cho HY. Iso-lation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis. Biol Pharm Bull. 2002;25(1):102-8.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">de Marino S., Borbone N., Zollo F., Ianaro A., Di Meglio P., Iorizzi M. Megastigmane and Phenolic Components from Laurus nobilis L. Leaves and Their Inhibitory Effects on Nitric Oxide Production // J. Agric. Food Chem. 2004. Vol. 52. P. 7525-7531.</mixed-citation><mixed-citation xml:lang="en">de Marino S, Borbone N, Zollo F, Ianaro A, Di Meglio P, Iorizzi M. Megastigmane and Phenolic Components from Laurus nobilis L. Leaves and Their Inhibitory Effects on Nitric Oxide Production. J Agric Food Chem. 2004;52:7525-31.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Skerget, M., Kotnik, P., Hadolin, M., Hras, A. R., Simonic, M., &amp; Knez, Z. (2005). Phenols, proanthocyanidins, flavones and flavonols in some plant materials and their antioxidant activities // Food chemistry, 89(2), 191-198.</mixed-citation><mixed-citation xml:lang="en">Skerget M, Kotnik P, Hadolin M, Hras AR, Simonic M, &amp; Knez Z. Phenols, proanthocyanidins, flavones and flavonols in some plant materials and their antioxidant activities. Food chemistry. 2005;89(2):191-8.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Longo, L., &amp; Vasapollo, G. (2005). Anthocyanins from bay (Laurus nobilis L.) berries // Journal of agricultural and food chemistry, 53(20), 8063-8067.</mixed-citation><mixed-citation xml:lang="en">Longo L, Vasapollo G. Anthocyanins from bay (Laurus nobilis L.) berries. Journal of agricultural and food chemistry. 2005;53(20), 8063-7.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Papageorgiou V., Mallouchos A., Komaitis M. Investigation of the Antioxidant Behavior of Air- and Freeze-Dried Aromatic Plant Materials in Relation to Their Phenolic Content and Vegetative Cycle // J. Agric. Food Chem. 2008. Vol. 56. P. 5743-5752.</mixed-citation><mixed-citation xml:lang="en">Papageorgiou V, Mallouchos A, Komaitis M. Investigation of the Antioxidant Behavior of Air- and Freeze-Dried Aro¬matic Plant Materials in Relation to Their Phenolic Content and Vegetative Cycle. J Agric Food Chem. 2008;56:5743-52.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Singleton, V. L., &amp; Rossi, J. A. (1965). Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. American journal of Enology and Viticulture, 16(3), 144-158.</mixed-citation><mixed-citation xml:lang="en">Singleton VL, Rossi JA. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. American journal of Enology and Viticulture. 1965;16(3):144-58.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Cannac, M.; Ferrat, L.; Barboni, T.; Pergent, G.; Pasqualini, V. The influence of tissue handling on the flavonoid content of the aquatic plant Posidonia oceanic // J. Chem. Ecol. 2007. Vol. 33. P. 1083-1088.</mixed-citation><mixed-citation xml:lang="en">Cannac M, Ferrat L, Barboni T, Pergent G, Pasqualini V. The influence of tissue handling on the flavonoid con¬tent of the aquatic plant Posidonia oceanic. J Chem Ecol. 2007;33:1083-8.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Moure, A.; Cruz, J. M.; Franco, D.; Dominguez, J. M.; Sineiro, J.; Dominguez, H.; Jose Nunez, M.; Parajo, J. C. Natural antioxidants from residuals sources // Food Chem. 2001. Vol. 72. P. 145-171.</mixed-citation><mixed-citation xml:lang="en">Moure A, Cruz JM, Franco D, Dominguez JM, Sineiro J, Dominguez H, Jose Nunez M, Parajo JC. Natural antioxidants from residuals sources. Food Chem. 2001;72:145-71.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Muchuweti, M., Kativu, E., Mupure, C. H., Chidewe, C., Ndhlala, A. R., Benhura, M. A. N. Phenolic composition and antioxidant properties of some spices // American Journal of Food Technology. 2007. Vol. 2, Is. 5. P. 414-420.</mixed-citation><mixed-citation xml:lang="en">Muchuweti M, Kativu E, Mupure CH, Chidewe C, Ndhlala AR, Benhura MAN. Phenolic composition and antioxidant properties of some spices. American Journal of Food Technology. 2007;2(5):414-20.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Unver, A., Arslan, D., Ozcan, M.M., Akbulut, M. Phenolic content and antioxidant activity of some spices // World Applied Sciences Journal. 2009. Vol. 6, Is. 3. P. 373-377.</mixed-citation><mixed-citation xml:lang="en">Unver A, Arslan D, Ozcan MM, Akbulut M. Phenolic con¬tent and antioxidant activity of some spices. World Applied Sciences Journal. 2009;6(3):373-7.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Lu, M., Yuan, B., Zeng, M., Chen, J. Antioxidant capacity and major phenolic compounds of spices commonly consumed in China // Food Research International. - 2011. Vol. 44, Is. 2. P. 530-536.</mixed-citation><mixed-citation xml:lang="en">Lu M, Yuan B, Zeng M, Chen J. Antioxidant capacity and major phenolic compounds of spices commonly consumed in China. Food Research International. 2011;44(2):530-6.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Lee, S., Chung, S.-Ch., Lee, S.-H., Park, W., Oh, I., Mar, W., Shin, J., Oh, K.-B. Acylated kaempferol glycosides from Laurus nobilis leaves and their inhibitory effects on Na+/ K+-adenosine triphosphatase // Biol. Pharm. Bull. 2012. Vol. 35, Is. 3. P. 428-432.</mixed-citation><mixed-citation xml:lang="en">Lee S, Chung SCh, Lee SH, Park W, Oh I, Mar W, Shin J, Oh KB. Acylated kaempferol glycosides from Laurus nobilis leaves and their inhibitory effects on Na+/K+-adenosine triphosphatase. Biol Pharm Bull. 2012;35(3):428-32.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Pacifico, S., Gallicchio, M., Lorenz, P., Duckstein, S.M., Potenza, N., Galasso, S., Marciano, S., Fiorentino, A., Stintzing, F.C., Monaco, P. Neuroprotective Potential of Laurus nobilis Antioxidant Polyphenol-Enriched Leaf Extracts // Chemical research in toxicology. 2014. Vol. 27, Is. 4. P. 611-626.</mixed-citation><mixed-citation xml:lang="en">Pacifico S, Gallicchio M, Lorenz P, Duckstein SM, Potenza N, Galasso S, Marciano S, Fiorentino A, Stintzing FC, Monaco P. Neuroprotective Potential of Laurus nobilis Antioxidant Polyphenol-Enriched Leaf Extracts. Chemical research in toxicology. 2014;27(4):611-26.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Dias, M.I., Barros, L., Duenas, M., Alves, R.C., Oliveira, M.B.P., Santos-Buelga, C., Ferreira, I.C. Nutritional and antioxidant contributions of Laurus nobilis L. leaves: would be more suitable a wild or a cultivated sample? // Food chemistry. 2014. Vol. 156. С. 339-346.</mixed-citation><mixed-citation xml:lang="en">Dias MI, Barros L, Duenas M, Alves RC, Oliveira MBP, Santos-Buelga C, Ferreira IC. Nutritional and antioxidant contributions of Laurus nobilis L. leaves: would be more suitable a wild or a cultivated sample? Food chemistry. 2014;156:339-46.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Dias, M.I., Barreira, J., Calhelha, R.C., Queiroz, M.J.R., Oliveira, M. B. P. P., Sokovic, M., Ferreira, I.C. Two-dimensional PCA highlights the differentiated antitumor and antimicrobial activity of methanolic and aqueous extracts of Laurus nobilis L. from different origins // BioMed research international. 2014. Vol. 2014. 10 p.</mixed-citation><mixed-citation xml:lang="en">Dias MI, Barreira J, Calhelha RC, Queiroz MJR, Oliveira MBPP, Sokovic M, Ferreira IC. Two-dimensional PCA high-lights the differentiated antitumor and antimicrobial activity of methanolic and aqueous extracts of Laurus nobilis L. from different origins. BioMed research international. 2014; 2014:10.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Muniz-Marquez, D.B., Martinez-Avila, G.C., Wong- Paz, J.E., Belmares-Cerda, R., Rodriguez-Herrera, R., Aguilar, C.N. Ultrasound-assisted extraction of phenolic compounds from Laurus nobilis L. and their antioxidant activity //Ultrasonics sonochemistry. 2013. Vol. 20, Is. 5. P. 1149-1154.</mixed-citation><mixed-citation xml:lang="en">Muniz-Marquez DB, Marti'nez-Avila GC, Wong-Paz JE, Belmares-Cerda R, Rodriguez-Herrera R, Aguilar CN. Ultra-sound-assisted extraction of phenolic compounds from Laurus nobilis L. and their antioxidant activity. Ultrasonics sonochemistry. 2013;20(5):1149-54.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Musienko, S.G., Kyslychenko, V.S. The quantitative content of the main groups of biologically active substances in the bay laurel raw material // Вкник Фармацп. 2014. №4(80). С. 22-24.</mixed-citation><mixed-citation xml:lang="en">Musienko SG, Kyslychenko VS. The quantitative content of the main groups of biologically active substances in the bay laurel raw material. Pharmacy Bulletin. 2014;4(80):22-4. Ukrainian.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Муаенко, С.Г., Кисличенко, В.С. Дослщження фенольних сполук сировини лавра благородного // Збiрник наукових праць ствробтниюв НМАПО iM. ПЛ Шупика. 2014. №. 23 (4). С. 341-344.</mixed-citation><mixed-citation xml:lang="en">Musienko SH, Kyslychenko VS. Study of phenolic compounds of raw bay laurel. Collection of scientific works of NMAPE em. PL Shupik. 2014;23(4):341-344. Ukrainian.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Vinha, A. F., Guido, L. F., Costa, A. S., Alves, R. C., &amp; Oliveira, M. B. P. (2015). Monomeric and oligomeric flavan-3-ols and antioxidant activity of leaves from different Laurus sp. Food &amp; function, 6(6), 1944-1949.</mixed-citation><mixed-citation xml:lang="en">Vinha AF, Guido LF, Costa AS, Alves RC, Oliveira MBP. Monomeric and oligomeric flavan-3-ols and antioxidant activity of leaves from different Laurus sp. Food &amp; function. 2015;6(6):1944-1949.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
