STUDY OF PINOSTROBIN INFLUENCE ON THE BEHAVOUR ACTIVITY AND PSYCHO-EMOTIONAL STATE OFANIMALS AGAINST THE BACKGROUND OF PHYSICAL AND PSYCHO-EMOTIONAL LOADS
https://doi.org/10.19163/2307-9266-2014-2-1(2)-42-46
Abstract
A perspective pharmacological approach for correction of functional disorders, connected with physical and psycho-emotional stresses is the application of substances with antioxidant activity including flavonoids. In this research it was studied the influence of pinostrobin in the dose 100mg/kg per os on the behavior state of rats. They modeled an intensive physical load by swimming of animals with the load wich is equal 5% from body mass during 7 days. The behavior state was estimated in the tests «an open field» and «a raised cross-haped labyrinth». The application of pinostrobin prevented for certain the reduction of motive and reference researching activity reduced the level of anxiety and fear of the animals that had intensive physical load, in comparison with the control group animals that had not a pharmacological support
About the Authors
A. V. Voronkov
Pyatigorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University, Pyatigorsk
Russian Federation
Russian Federation
N. A. Mouraviova
Pyatigorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University, Pyatigorsk
Russian Federation
Russian Federation
I. N. Diakova
Pyatigorsk Medical and Pharmaceutical Institute - a branch of Volgograd State Medical University, Pyatigorsk
Russian Federation
Russian Federation
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Review
For citations:
Voronkov A.V., Mouraviova N.A., Diakova I.N. STUDY OF PINOSTROBIN INFLUENCE ON THE BEHAVOUR ACTIVITY AND PSYCHO-EMOTIONAL STATE OFANIMALS AGAINST THE BACKGROUND OF PHYSICAL AND PSYCHO-EMOTIONAL LOADS. Pharmacy & Pharmacology. 2014;2(1(2)):42-46. (In Russ.) https://doi.org/10.19163/2307-9266-2014-2-1(2)-42-46
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