BIOLOGICAL ACTIVITY OF THE COMPONENTS OF ROYAL JELLY AND BEE VENOM
https://doi.org/10.19163/2307-9266-2018-6-5-419-439
Abstract
Both bee products themselves and their combinations are widely represented in the domestic pharmaceutical market, however, modern experimental studies of the biological activity of these compounds are few, and in many of the existing publications the authors describe an extremely wide and controversial range of therapeutic effects. The aim of the study is to analyze the experimental works on the study of biological activity of bee products. Materials and methods. The study was conducted using search and information (eLibrary, PubMed, CyberLeninka, ResearchGate) and library databases (Russian State Library, Central Scientific Agricultural Library). In the designated databases, publications were searched by such terms as “biological activity”, “royal jelly”, etc. The depth of the search was not limited. Results and discussion. The analysis of the published works shows that such substances as bee venom and royal jelly have experimentally confirmed their biological activity. In both cases, the active substances have been described and a review of their detected biological activity has been carried out. Conclusion. The authors suggest that when developing the method of laboratory synthesis of decene acids, it can be possible to carry out their large-scale preclinical research, which may become the basis for the creation of a drug with a selective effect.
About the Authors
S. G. Mardanly
State University of Humanities and Technology;
CJSC “Ecolab”
Russian Federation
Russian Federation
Mardanly Seyfaddin Gashimovich – Professor of the Department of Pharmacology and Pharmaceutical Disciplines, Doctor of Medicine, Honored Employee of Health of the Russian Federation.
SPIN-code: 8284-0411, AuthorID: 772550.
22, Zelenaya Str., Orekhovo-Zuyevo, Moscow region, Russia, 142600;
1, Budenny Str, Elektrogorsk, Moscow region, Russia, 142530.
V. V. Pomazanov
State University of Humanities and Technology;
CJSC “Ecolab”
Russian Federation
Russian Federation
Pomazanov Vladimir Vasilyevich – Doctor of Technical Sciences, Professor of the Department of Pharmacology and Pharmaceutical Disciplines, President of the Association of chromatographists n.a. MS Tsvet, an expert in the field of physico-chemical methods for analyzing complex mixtures of natural and artificial origin.
SPIN-code: 3200-2407, AuthorID: 603793.
22, Zelenaya Str., Orekhovo-Zuyevo, Moscow region, Russia, 142600;
1, Budenny Str, Elektrogorsk, Moscow region, Russia, 142530.
V. A. Kiseleva
State University of Humanities and Technology
Russian Federation
Russian Federation
Kisileva Valentina Alekseevna – Candidate of Sciences (Medicine), Associate Professor of the Department of Pharmacology and Pharmaceutical Disciplines, State Educational Institution of Higher Education of the Moscow Region, Dean of the Faculty of Pharmacy.
SPIN-code: 3412-2916, AuthorID: 342898
22, Zelenaya Str., Orekhovo-Zuyevo, Moscow region, Russia, 142600
Ya. B. Neskorodov
CJSC “Ecolab”
Russian Federation
Russian Federation
Neskorodov Yaroslav Borisovich - Candidate of Sciences (Biology). Researcher of the company ECO Lab.
SPIN-code: 4104-2520, AuthorID: 630791.
1, Budenny Str, Elektrogorsk, Moscow region, Russia, 142530
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Review
For citations:
Mardanly S.G., Pomazanov V.V., Kiseleva V.A., Neskorodov Ya.B. BIOLOGICAL ACTIVITY OF THE COMPONENTS OF ROYAL JELLY AND BEE VENOM. Pharmacy & Pharmacology. 2018;6(5):419-439. (In Russ.) https://doi.org/10.19163/2307-9266-2018-6-5-419-439
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