A NEW AYAFROL PHYTOPREPARATION BIOACCESSIBILITY STUDY
https://doi.org/10.19163/2307-9266-2014-2-6(7)-62-65
Abstract
The articles describes the results of "Ayafrol, 3% ointment" phytopreparation bioaccessibility study on the basis of essential oil of Ajania fruticulosa for local treatment of wounds. We have studied pharmacokinetics of the phytopreparation with estimation of intensity of essential oil components general action on organism after its penetration in systemic blood. The method is based on isolated liquid extraction of substances from serum of experimental animals. The results showed that there was no cumulation of phytopreparation components in system blood in 24 hours exposition while applying it locally. High concentration of a substance may occur directly on the wound surface. Thus Ayafrol ointment components are oriented on a local action towards wounds, directly in a place of contact of wound surface
About the Authors
S. M. Adekenov
Fitohimiya” International scientific and manufacturing holding, Karaganda, Kazakhstan
Russian Federation
Russian Federation
E. M. Turgunov
Karaganda State Medical University, Karaganda, Kazakhstan
Russian Federation
Russian Federation
G. A. Atazhanova
Fitohimiya” International scientific and manufacturing holding, Karaganda, Kazakhstan
Russian Federation
Russian Federation
I. S. Azizov
Karaganda State Medical University, Karaganda, Kazakhstan
Russian Federation
Russian Federation
V. S. Tritek
Life Sciences Center, Nazarbaev University, Astana, Kazakhstan
Russian Federation
Russian Federation
R. M. Badyrov
Karaganda State Medical University, Karaganda, Kazakhstan
Russian Federation
Russian Federation
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Review
For citations:
Adekenov S.M., Turgunov E.M., Atazhanova G.A., Azizov I.S., Tritek V.S., Badyrov R.M. A NEW AYAFROL PHYTOPREPARATION BIOACCESSIBILITY STUDY. Pharmacy & Pharmacology. 2014;2(6(7)):62-65. (In Russ.) https://doi.org/10.19163/2307-9266-2014-2-6(7)-62-65
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