Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles | Puchenkova | Pharmacy & Pharmacology

Pharmacy & Pharmacology
Farmaciâ i farmakologiâ

ISSN 2307-9266 (Print)
ISSN 2413-2241 (Online)

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Puchenkova O.A., Shheblykina O.V., Kostina D.A., Bolgov A.A., Lebedev P.R., Molchanov V.V., Pokrovskaya T.G., Korokin M.V., Nikiforov E.A., Vaskina N.F., Idrisov T.A., Moseev T.D., Melekhin V.V., Varaksin M.V., Charushin V.N., Chupakhin O.N. Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles. Pharmacy & Pharmacology. 2024;12(6):394-409. (In Russ.) https://doi.org/10.19163/2307-9266-2024-12-6-394-409

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ISSN 2307-9266 (Print)
ISSN 2413-2241 (Online)

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About the Authors

O. A. Puchenkova
Belgorod State National Research University
Russian Federation

postgraduate student of the Department of Pharmacology and Clinical Pharmacology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

O. V. Shheblykina
Belgorod State National Research University
Russian Federation

Candidate of Sciences (Medicine), Assistant Professor of the Department of Pharmacology and Clinical Pharmacology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

D. A. Kostina
Belgorod State National Research University
Russian Federation

Candidate of Sciences (Medicine), Assistant Professor of the Department of Pharmacology and Clinical Pharmacology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

A. A. Bolgov
Belgorod State National Research University
Russian Federation

postgraduate student of the Department of Pathology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

P. R. Lebedev
Belgorod State National Research University
Russian Federation

junior researcher of the Laboratory of Genetic Technologies and Gene Editing for Biomedicine and Veterinary Medicine of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

V. V. Molchanov
Belgorod State National Research University
Russian Federation

postgraduate student of the Department of Pharmacology and Clinical Pharmacology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

T. G. Pokrovskaya
Belgorod State National Research University
Russian Federation

Doctor of Sciences (Medicine), Assistant Professor, Professor of the Department of Pharmacology and Clinical Pharmacology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

M. V. Korokin
Belgorod State National Research University
Russian Federation

Doctor of Sciences (Medicine), Assistant Professor, Professor of the Department of Pharmacology and Clinical Pharmacology of the Belgorod State National Research University.

85 Pobedy Str., Belgorod, Russia, 308015.

E. A. Nikiforov
Federal University named after the First President of Russia B.N. Yeltsin
Russian Federation

Research Engineer at the Laboratory of Advanced Materials, Green Methods and Biotechnologies of the Scientific, Educational and Innovative Center for Chemical and Pharmaceutical Technologies of the Institute of Chemical Technology, Federal University named after the First President of Russia B.N. Yeltsin.

19 Mira Str., Yekaterinburg, Russia, 620062.

N. F. Vaskina
Federal University named after the First President of Russia B.N. Yeltsin
Russian Federation

Laboratory researcher at the Department of Organic and Biomolecular Chemistry of the Institute of Chemical Technology of the Federal University named after the First President of Russia B.N. Yeltsin.

19 Mira Str., Yekaterinburg, Russia, 620062.

T. A. Idrisov
Federal University named after the First President of Russia B.N. Yeltsin
Russian Federation

Research Engineer at the Laboratory of Advanced Materials, Green Methods and Biotechnologies of the Scientific, Educational and Innovative Center for Chemical and Pharmaceutical Technologies of the Institute of Chemical Technology, Federal University named after the First President of Russia B.N. Yeltsin.

19 Mira Str., Yekaterinburg, Russia, 620062.

T. D. Moseev
Federal University named after the First President of Russia B.N. Yeltsin
Russian Federation

Candidate of Sciences (Chemistry), Assistant Professor of the Scientific, Educational and Innovative Center for Chemical and Pharmaceutical Technologies of the Institute of Chemical Technology, Federal University named after the First President of Russia B.N. Yeltsin.

19 Mira Str., Yekaterinburg, Russia, 620062.

V. V. Melekhin
1. Federal University named after the First President of Russia B.N. Yeltsin. 2. Ural State Medical University.
Russian Federation

Candidate of Sciences (Medicine), Head of the Laboratory of Primary Screening, Cellular and Gene Technologies of the Scientific, Educational and Innovative Center for Chemical and Pharmaceutical Technologies of the Institute of Chemical Technology, Federal University named after the First President of Russia B.N. Yeltsin.

1. 19 Mira Str., Yekaterinburg, Russia, 620062.

2. 3 Repin Str., Yekaterinburg, Russia, 620028.

M. V. Varaksin
1. Federal University named after the First President of Russia B.N. Yeltsin. 2. Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences.
Russian Federation

Doctor of Sciences (Chemistry), Professor of the Department of Organic and Biomolecular Chemistry, leading researcher of the Laboratory of Advanced Materials, Green Methods and Biotechnologies of the Scientific, Educational and Innovative Center for Chemical and Pharmaceutical Technologies of the Institute of Chemical Technology, Federal University named after the First President of Russia B.N. Yeltsin; researcher of the Laboratory of Coordination Compounds of the Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences.

1. 19 Mira Str., Yekaterinburg, Russia, 620062.

2. 22/20 Sofya Kovalevskaya / Akademicheskaya Str., Yekaterinburg, Russia, 620137

V. N. Charushin
1. Federal University named after the First President of Russia B.N. Yeltsin. 2. Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences.
Russian Federation

Doctor of Sciences (Chemistry), Professor of the Department of Organic and Biomolecular Chemistry of the Institute of Chemical Technology of the Federal University named after the First President of Russia B.N. Yeltsin; chief researcher, Head of the Laboratory of Heterocyclic Compounds of the Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences; Academician of the Russian Academy of Sciences.

1. 19 Mira Str., Yekaterinburg, Russia, 620062.

2. 22/20 Sofya Kovalevskaya / Akademicheskaya Str., Yekaterinburg, Russia, 620137.

O. N. Chupakhin
1. Federal University named after the First President of Russia B.N. Yeltsin. 2. Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences.
Russian Federation

Doctor of Sciences (Chemistry), Professor of the Department of Organic and Biomolecular Chemistry of the Institute of Chemical Technology of the Federal University named after the First President of Russia B.N. Yeltsin; Head of the Laboratory of Coordination Compounds of the Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences; Academician of the Russian Academy of Sciences.

1. 19 Mira Str., Yekaterinburg, Russia, 620062.

2. 22/20 Sofya Kovalevskaya / Akademicheskaya Str., Yekaterinburg, Russia, 620137.

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