HIGH PERFORMANCE LIQUID CHROMATOGRAPHY USE IN ANALYSIS OF SESQUITERPENIC LACTONES OF LAURUS NOBILIS
https://doi.org/10.19163/2307-9266-2015-3-1(8)-46-49
Abstract
We have developed a methodology of quantitative determination of sesquiterpenic lactones (costunolide and dehydrocostuslactone) in leaves of Laurus nobilis using reversed phase HPLC. We have determined optimal conditions for the substances under study extraction from active parts. Using the developed methods we have established that costunolide and dehydrocostuslactone content in Laurus nobilis samples in terms of absolutely dry active parts is 0.99 and 0.26% correspondingly.
About the Authors
S. P. Senchenko
Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University, Pyatigorsk
Russian Federation
Russian Federation
N. M. Nasukhova
Dagestan State University, Makhachkala
Russian Federation
Russian Federation
L. A. Agova
Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University, Pyatigorsk
Russian Federation
Russian Federation
D. A. Konovalov
Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical University, Pyatigorsk
Russian Federation
Russian Federation
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Review
For citations:
Senchenko S.P., Nasukhova N.M., Agova L.A., Konovalov D.A. HIGH PERFORMANCE LIQUID CHROMATOGRAPHY USE IN ANALYSIS OF SESQUITERPENIC LACTONES OF LAURUS NOBILIS. Pharmacy & Pharmacology. 2015;3(1(8)):46-49. (In Russ.) https://doi.org/10.19163/2307-9266-2015-3-1(8)-46-49
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