Under review is Salix babylonica L., which is widely cultivated in Russia as an ornamental plant. The purpose of the review is to summarize the literature on the chemical composition and pharmacological activity of the Babylonian willow. In Russia, only the qualitative composition of the studied species studied, pharmacologi-cal studies have not been conducted. Abroad, there is a positive experience of Salix babylonica in folk medicine, and obtained results that indicate a high content of biologically active compounds. Shown in the survey data suggest the prospect of studying the Babylonian willows growing in the southern regions of Russia for use in medicine and pharmacy.

Search for new applications of known drugs is unique among methods of finding drugs. Significant sav-ings is the benefit of this approach. Known drugs are well studied, change their application does not require ex-tensive research accompanying the introduction of the pharmaceutical market of new substances. In this paper, an example of extending the scope of known drugs is shown by the example of promising research in a number of well-known disaggregants drugs using techniques of molecular modeling, quantum chemistry and multivariate statistical analysis.

Determination results of impurities verapamil hydrochloride and lisinopril dihydrate using computer modeling and HPLC coupled with mass spectrometry (HPLC-MS) reported in this article. Prediction and calcu-lation of the thermodynamic characteristics of the substances carried by the method of RM1 and programs HyperChem. Mass spectrometric analysis was performed on a quadrupole mass analyzer in the recording mode of the positive ions within the range m / z 100-1000. The study found that described in the regulations extrane-ous verapamil and lisinopril are the products of degradation of materials. Prediction of degradation products of lisinopril dihydrate fully confirmed the data of the ion current chromatograms and mass spectra of the substanc-es. However, in the case of verapamil simulation results coincided with the degradation products by HPLC-MS analysis for two of the four predicted substances

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The article presents information on the formation Botanical Garden at Pyatigorsk Pharmaceutical Insti-tute, the history of its formation, the current status of the collection. Indicated perspective directions of develop-ment the Botanical Garden as a scientific and cultural center of Pyatigorsk.

Especially the provision of pharmaceutical care to servicemen and civilian victims of terrorist acts, are studied in terms of rehabilitation treatment on the example of the branch "Pyatigorsk" sanatorium resort "The North" of the Ministry of Defense. Sanatorium treatment of persons with traumatic lesions of the nerve root and plexus is a complex that includes spa therapy in the form of baths, mud, mineral water and medicines for the relief of pain. With limited financing a number of problems that require solutions for high-quality medical and psychological rehabilitation of victims in emergency situations. According to a study developed regulations on the organization of nursing and pharmacy functional staff responsibilities due to changes in the scope and con-tent of their work duties in the present conditions

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The analysis of the range of the medicines presented by the pharmaceutical company «Servier » in the Russian market, applied is carried out at treatment of a wide range of diseases. The expert assessment of a pharmacoepidemiology approach is carried out during the developing, introduction and a promotion of medi-cines. Adaptation of innovative methods of formation of product range and the range taking into account a pharmacoepidemiology for domestic pharmaceutical companies is made.

A phytochemical study has been conducted to explore Agastache foeniculum (Lamiaceae), which is widely used in oriental medicine for colds, inflammation of the gastrointestinal tract and urinary system; exter-nally for fungal dermatitis, seborrhea, hair growth and strengthening. In the course of the experiment methods of chemical (such as alkalimetry, permanganatometriya, chelatometry) and physico-chemical (such as mass spec-trometry coupled with GC, differential UV spectrophotometry, HPLC, planar chromatography) analysis have been applied. The established range of biologically active compounds, especially essential oils and phenolic compounds, indicates the possibility of using Agastache foeniculum herb as a raw material source for producing drugs with antioxidant, antimicrobial, antimycotic and pilotropnym effect

Increasing attention is being given in the official medicine use of plant origin for the prevention and treatment of early stages of disorders of the cardiovascular system, including oxycinnamic acids. The flow rate of cerebral blood flow were recorded by the standard method using hydrogen clearance implanted platinum elec-trodes placed on the surface of brain sagittal sinus drain region in the sinuses. Caffeic and ferulic acid in the course application significantly increase the level of cerebral blood flow rate in the animals in the experimental rules. Caffeic and ferulic acid at course prophylactic use for 14 days significantly reduced the severity of cere-brovascular pathological phenomena (hyperperfusion and hypoperfusion), which significantly reduces the risk of tissue edema of the nervous system during the first phase - hyperperfusion and also reduces the mortality rate of animals during the second phase - hypoperfusion.

A promising approach for the correction of functional disorders associated with fatigue, is the use of an-tioxidant resources, particularly flavonoids. Therefore, the aim is to study the influence of Antistax a dose of 100 mg / kg per os on the performance and portability of intense exercise in rats. Intense exercise simulated swim-ming animals with a load equal to 5% of body weight for 7 days. Physical performance was evaluated on a long voyage. Application Antistax significantly increased the efficiency of the animals after intense exercise com-pared with the control groups and the intact animal

Based on the measured IR and H1NMR spectra of the substance 4-amino-3-(3-pyridyl)-butanoic acid dihydrochlorid carried interpretation of absorption and structural fragments installed analyte. The results led to the recommendation of these research methods to be used in pharmaceutical analysis as a substance and a drug for structure determination and identification of the substance.

Studies of quality of products of complex processing mud of Tambukan: press, alcohol and oil extrac-tions performed. The presence of humic acid and dehydrating the alcohol extraction of carotenoids and chloro-phyll in the oil alcoholic extraction of phytosterols in oil extraction using qualitative reactions, TLC, UV spec-trophotometry