The article presents data on the content of phenolics and rosmarinic acid in 32 species of aromatic and medicinal plants from Lamiaceae, Asteraceae and Apiaceae families, native to the South Coast of the Crimea. The concentration of phenolic compounds in the studied species was 490.3 – 18511.0 mg/100g of plant raw materials. Rosmarinic acid was found in 15 species from Lamiaceae and Asteraceae families. Rosmarinic acid was not noticed in the studied plants from Apiaceae family. The concentration of rosmarinic acid in the studied plants amounted to 40.6 – 2535.5 mg/100g of plant raw materials. On the basis of the obtained results such species as Origanum vulgare L., Majorana hortensis Moench., Mentha longifolia L., Thymus vulgaris L. (thymol type) can be considered as a promising source of rosmarinic acid.

Qualitative and quantitative composition of phenolcarbonic acids in one year tendrils of Salix triandra L. was determined. Identification in quantitative determination of certain phenolcarbonic acids was carried out using high-performance liquid chromatography. Six individual substances were discovered. The total content of the sum of phenolcarbonic acids was determined with extractionphotometric method, based on a selective extraction from acidulous solution into ethyl acetate. The highest content of phenolcarbonic acids (about 0.47%) was detected in the leaves of Salix triandra L., the lowest content was detected in the tendrils without leaves (about 0.40%). Phenolcarbonic acids discovered in the tendrils of Salix triandra L. may significantly contribute to the total pharmacological effect.

The article discusses the results of antiox-idaut activity of berries extract of Moms nigra L., Moras alba L., and Moras rubra L. We have studied the total content of antioxidants in the extract of these species beiiies using liquid chromotographer "Tsvet Yauza-01-AA". Aniperometric method was used for measuring of mass concentration of antioxidants. We determined the quantity of antioxidants using analytical curve of dependence of exit signal on the quercetine and gallic acid concentration. The study resulted on the revelation of antioxidant content in alcohol, water-alcohol, and water extracts from the objects of study mentioned above

The article presents active parts of Tribulus terrestris L. as a perspective sample for study. We have provided an example of flavo-noids determination with high-performance liquid chromatography / MS at the Waters Acquility chromatographer with tandem quad-rupolar MS-detector TQD (Waters).

То elaborate the composition of the suppositories with riboxiniirn we have studied physical and chemical, and structural and mechanical characteristics of different bases. Witepsol-H15 was chosen as a preferable base. We have carried out the quality estimation of the developed suppositories in accordance with regulatory documentation. The analysis methods offered are validated and proved to be specific, right and precise. The relative error of analysis is equal to ±0.98%. Supposito-ries with riboxinum at dose 15 mg/kg shows signified hepatoprotective action at white rats with experimental acute toxic hepatitis evoked by carbon tetrachloride injection, which ex-ceeds the similar pills effect

One of the indices of industrial waste safety including distillers grains is chemical oxygen demand (COD), and its value (53591÷64184 mg O/dm3) shows that it can be considered as unsustainable waste. This high value of COD is conditioned by the absence of toxins in distillers grains, and by concentration of biologically active substances after which isolation the distillers grains index lowers by 74%. This allows considering the distillers grains as environmentally safe. The results received evidence the necessity for consideration of COD index only as an index of oxidized substances, but not the criteria of waste pollution.

The search for available and at the effective method of quantitative determination of Baicalin in liquid complex phyto-extraction was the purpose of this work. The article shows experimental data of quantitative determination of Baicalin, received with densitometry. The method was validated, therefore there is an opportunity of its use for identification and quantitative determination of Baicalin in plants active parts.

The article presents the data about the possibility of joint use of vinpocetine with amber acid, solubility of vinpocetine improvement and the methods of their analysis in joint use.

Morphological parameters of the capillaries (diameter, linear and volumetric bloodflow rate, capillary network density) were evaluated in children and adolescents aged 12 to 15 years with normal occlusion and dentoalveolar anomalies using the computer capillaroscopy device KK 4-01 (“TSAV” JSC Center “Analiz veschestv”). We have also carried out a visual assessment of the microcirculation. The patients with jaw-bones hypoplasia and crowded teeth revealed deeper location of the arterioles and venules and reduced morphometric parameters of tissue blood flow, thus it indicates signified rheological disorders at the early stages of atrophic processes in the periodontal tissues.

Laser Doppler flowmetry was used to investigate the palatal muscosa capillary bloodflow in children aged 4.5-9 years with crowded teeth undergoing treatment with removable orthodontic appliances from cold-cured base polymers. The results obtained from the examination of the capillary blood flow based on the amplitude standard deviation, the variation coefficient, the amplitudes of vasomotor, breathing, and cardiorhythms, as well as the indices for active and passive mechanisms of blood flow modulation at the areas under study, showed that the hemodynamics indices in the palatal muscosa got disturbed a month after the treatment was started while the disturbances went even worse at later stages

We have carried out an experimental study of dose-dependent gastroprotective activity of transdermal plaster with ethylmethylhydroxypyridine succinate (mexidol), the purpose of which was the histological study of gastric mucosa, determination of lipid peroxidation (LP) in gastric tissue supernatant, weight study of thymus, spleen, and adrenals. Ethylmethylhydroxypyridine succinate has gastroprotective action in transdermal implementation at 20-75 mg/kg dose on the model of 18-hour immobilization of animals which had been starving for 24 hours.

The article is devoted to the problem of phytotherapy pharmaceutical services quality estimation support at the Caucasian Mineral Waters resorts on the basis of quality nianagement

Correctly organized nutritive and pharmacological support is an important component of an athlete's preparation for competitions, an optimal shape maintenance, fast recovery and rehabilitation after traumas and defatigation. Special products of enhanced biological value (BAS for athletes nutrition) are used with this purpose. Easy-to-use energy sources are administered into athlete's organism, yielded materials and biologically active substances which regulate and activate exchange reactions which proceed with difficulties during certain physical trainings. The article presents sport supplements classification which can be used before warm-up and trainings, after trainings and in competitions breaks.